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Article

Infective Larvae of Brugia malayi Induce Polarization of Host Macrophages that Helps in Immune Evasion.

Frontiers in immunology - 1 Jan 2018

Sharma Aditi, Sharma Pankaj, Ganga Laxmi, Satoeya Neha, Mishra Shikha, Vishwakarma Achchhe Lal, Srivastava Mrigank

Abstract excerpt

Filarial parasites suppress, divert, or polarize the host immune response to aid their survival. However, mechanisms that govern the polarization of host MΦs during early filarial infection are not completely understood. In this study, we infected BALB/c mice with infective larvae stage-3 of Brugia malayi (Bm-L3) and studied their effect on the polarization of splenic MΦs. Results showed that MΦs displayed...

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Identifiers

PMID: 29483912
DOI: 10.3389/fimmu.2018.00194
PMCID: PMC5816041

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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