Phenotype, function, and differentiation potential of human monocyte subsets.

doi:10.1371/journal.pone.0176460

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Article

Phenotype, function, and differentiation potential of human monocyte subsets.

PloS one - 1 Jan 2017

Boyette Lisa B, Macedo Camila, Hadi Kevin, Elinoff Beth D, Walters John T, Ramaswami Bala, Chalasani Geetha, Taboas Juan M, Lakkis Fadi G, Metes Diana M

Abstract excerpt

Human monocytes have been grouped into classical (CD14++CD16-), non-classical (CD14dimCD16++), and intermediate (CD14++CD16+) subsets. Documentation of normal function and variation in this complement of subtypes, particularly their differentiation potential to dendritic cells (DC) or macrophages, remains incomplete. We therefore phenotyped monocytes from peripheral blood of healthy subjects and performed...

Topics

Cell Differentiation
Cells, Cultured
Dendritic Cells
Granulocyte-Macrophage Colony-Stimulating Factor
Humans
Immunophenotyping
Interleukin-1beta
Interleukin-6
Macrophage Colony-Stimulating Factor
Macrophages

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Microscopy, Fluorescence

Monocytes

Phagocytosis

Phenotype

Toll-Like Receptors

Tumor Necrosis Factor-alpha

Source

Open in PubMed Open full text

Identifiers

PMID: 28445506
DOI: 10.1371/journal.pone.0176460
PMCID: PMC5406034

Genes

TLR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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