Article
Apathy is associated with a single-nucleotide polymorphism in a dopamine-related gene.
Neuroscience letters - 9 Aug 2013
Mitaki Shingo, Isomura Minoru, Maniwa Kyohei, Yamasaki Masayuki, Nagai Atsushi, Nabika Toru, Yamaguchi Shuhei
Abstract excerpt
Dopaminergic neurotransmission is an important factor in the pathogenesis of apathy. In addition, the contribution of genetic factors to the regulation of brain dopaminergic activity is widely acknowledged. Therefore, we hypothesized that genes associated with brain dopaminergic activity may have some effects on apathy. In the current study, we evaluated the association between four functional single-nucleotide...
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