Article
Further analysis of the lens phenotype in Lim2-deficient mice.
Investigative ophthalmology & visual science - 21 Sept 2011
Shi Yanrong, De Maria Alicia B, Wang Huan, Mathias Richard T, FitzGerald Paul G, Bassnett Steven
Abstract excerpt
PURPOSE: Lim2 (MP20) is the second most abundant integral protein of lens fiber cell membranes. A comparative analysis was performed of wild-type and Lim2-deficient (Lim2(Gt/Gt)) mouse lenses, to better define the anatomic and physiologic roles of Lim2. METHODS: Scanning electron microscopy (SEM) and confocal microscopy were used to assess the contribution of Lim2 to lens tissue architecture....
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