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Article

Nuclear envelope protein Lem2 is required for mouse development and regulates MAP and AKT kinases.

PloS one - 1 Jan 2015

Tapia Olga, Fong Loren G, Huber Michael D, Young Stephen G, Gerace Larry

Abstract excerpt

The nuclear lamina, along with associated nuclear membrane proteins, is a nexus for regulating signaling in the nucleus. Numerous human diseases arise from mutations in lamina proteins, and experimental models for these disorders have revealed aberrant regulation of various signaling pathways. Previously, we reported that the inner nuclear membrane protein Lem2, which is expressed at high levels in muscle,...

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Identifiers

PMID: 25790465
DOI: 10.1371/journal.pone.0116196
PMCID: PMC4366207

Genes

LEMD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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