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Article

Refractive defects and cataracts in mice lacking lens intrinsic membrane protein-2.

Investigative ophthalmology & visual science - 1 Feb 2007

Shiels Alan, King Jennifer M, Mackay Donna S, Bassnett Steven

Abstract excerpt

PURPOSE: To characterize the optical properties of lenses from mice deficient in the gene for lens intrinsic membrane protein-2 (Lim2), which encodes the second most abundant integral protein (Lim2) of lens fiber cell plasma membranes. METHODS: Lim2-deficient mice were derived from a library of gene-trap embryo stem cells. Genotyping was performed by polymerase chain reaction (PCR) amplification of tail genomic...

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Source

Identifiers

PMID: 17251442
DOI: 10.1167/iovs.06-0947

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Refractive defects and cataracts in mice lacking lens intrinsic membrane protein-2.PMID 17251442Read ↗

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