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Article

Keratinocyte migration in the developing eyelid requires LIMK2.

PloS one - 1 Jan 2012

Rice Dennis S, Hansen Gwenn M, Liu Feng, Crist Mike J, Newhouse Matthew M, Potter David, Xu Nianhua, Abuin Alejandro, Vogel Peter J, Zambrowicz Brian P

Abstract excerpt

In vitro studies have identified LIMK2 as a key downstream effector of Rho GTPase-induced changes in cytoskeletal organization. LIMK2 is phosphorylated and activated by Rho associated coiled-coil kinases (ROCKs) in response to a variety of growth factors. The biochemical targets of LIMK2 belong to a family of actin binding proteins that are potent modulators of actin assembly and disassembly. Although numerous...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 23071748
DOI: 10.1371/journal.pone.0047168
PMCID: PMC3465268

Genes

LIMK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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