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Article

Production of TNF-α and IL-1β by peripheral blood mononuclear cells in carriers of different allele variants of the gene.

Bulletin of experimental biology and medicine - 1 May 2012

Silkov A N, Sennikova N S, Goreva E P, Lopatnikova Yu A, Sennikov S V

Abstract excerpt

Associations of cytokine production by mononuclear cells and the TNF-α genetic polymorphism in positions -238, -308, -376, -857, -1031, and of IL-1β in positions -31 and +3954 were studied. The data on distribution of allele and genotype incidence and on the level of spontaneous and mitogen-induced production of these cytokines by donor mononuclear cells demonstrated a statistically significant association of...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Interleukin-1beta

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Share to Polymorphism, Genetic

Share to Promoter Regions, Genetic

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Source

Identifiers

PMID: 22808497
DOI: 10.1007/s10517-012-1646-3

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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