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Article

Cyclic-AMP-responsive transcriptional activation of CREB-327 involves interdependent phosphorylated subdomains.

The EMBO journal - 1 Dec 1990

Lee C Q, Yun Y D, Hoeffler J P, Habener J F

Abstract excerpt

Cyclic AMP-regulated gene expression is mediated by specific phosphoproteins (CREBs) which bind to cAMP-responsive elements of gene promoters. By analyzing the transactivation activities and phosphorylations in vivo of deletion and point mutated chimeric fusion proteins of the placental CREB-327, in which the DNA-binding domain is replaced by the heterologous binding-domain of the yeast transcription factor GAL4,...

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Identifiers

PMID: 2176153
DOI: 10.1002/j.1460-2075.1990.tb07896.x
PMCID: PMC552238

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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