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Article

Electrostatic control of half-site spacing preferences by the cyclic AMP response element-binding protein CREB.

Nucleic acids research - 15 Aug 2001

Montclare J K, Sloan L S, Schepartz A

Abstract excerpt

Basic region leucine zipper (bZIP) proteins represent a class of transcription factors that bind DNA using a simple, dimeric, alpha-helical recognition motif. The cAMP response element-binding protein (CREB) is a member of the CREB/ATF subfamily of bZIP proteins. CREB discriminates effectively in vivo and in vitro between the 10 bp cAMP response element (ATGACGTCAT, CRE) and the 9 bp activating protein 1 site...

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Identifiers

PMID: 11504868
DOI: 10.1093/nar/29.16.3311
PMCID: PMC55852

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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