Article
Cyclic AMP induction of phosphoenolpyruvate carboxykinase (GTP) gene transcription is mediated by multiple promoter elements.
The Journal of biological chemistry - 5 Oct 1991
Liu J S, Park E A, Gurney A L, Roesler W J, Hanson R W
Abstract excerpt
The cis elements involved in the cAMP regulation of transcription of the gene for phosphoenolpyruvate carboxykinase (GTP) (EC 4.1.1.32) (PEPCK) were studied by introducing a series of block mutations (10-15 base pairs of random sequence) into eight of the protein binding domains in a region of th...
Topics
- Base Sequence
- Cloning, Molecular
- Cyclic AMP
- DNA
- Enzyme Induction
- Escherichia coli
- Gene Expression Regulation, Enzymologic
- Genetic Vectors
- Humans
- Molecular Sequence Data
- Mutation
- Phosphoenolpyruvate Carboxykinase (GTP)