TP53 status and response to treatment in breast cancers.

doi:10.1155/2011/284584

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Article

TP53 status and response to treatment in breast cancers.

Journal of biomedicine & biotechnology - 1 Jan 2011

Varna Mariana, Bousquet Guilhem, Plassa Louis-François, Bertheau Philippe, Janin Anne

Abstract excerpt

The p53 wild-type protein plays an important role in cells as is shown by its fine regulation at different levels. Since its discovery, numerous mutations have been described. In breast cancers, p53 is mutated in almost 30% of cases, with a higher frequency in some tumor subtypes. TP53 mutation is reported to be a factor for good prognosis in some studies, while in others it is a factor for poor prognosis. The...

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PMID: 21760703
DOI: 10.1155/2011/284584
PMCID: PMC3114547

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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