Article
p53 Mutation as Plausible Predictor for Endocrine Resistance Therapy in Luminal Breast Cancer.
F1000Research - 1 Jan 2022
Halim Freda, Azhar Yohana, Suwarman Suwarman, Hernowo Bethy
Abstract excerpt
Endocrine therapy resistance in Luminal Breast Cancer is a significant issue to be tackled, but currently, no specific biomarker could be used to anticipate this event. p53 mutation is widely known as one of Breast Cancer's most prominent genetic alterations. Its mutation could generate various effects in Estrogen Receptor and Progesterone Receptor molecular works, tangled in events leading to the aggravation of...
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