Article
Differences in prognosis and efficacy of chemotherapy by p53 expression in triple-negative breast cancer.
Breast cancer research and treatment - 1 Nov 2018
Bae Soo Youn, Nam Seok Jin, Jung Yongsik, Lee Sae Byul, Park Byung-Woo, Lim Woosung, Jung Sung Hoo, Yang Hsien Wen, Jung Seung Pil
Abstract excerpt
PURPOSE: TP53 mutation is the most common mutation in breast cancer, and it is considered a target marker of triple-negative breast cancer (TNBC). We investigated whether expression of p53 detected by immunochemical staining predicts the chemotherapy response of TNBC. METHODS: A total of 11,393 TNBC patients who had between stage I and stage III enrolled in the Korean Breast Cancer Society Registry database from...
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