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Article

TP53 Mutations in Breast and Ovarian Cancer.

Cold Spring Harbor perspectives in medicine - 3 Jan 2017

Silwal-Pandit Laxmi, Langerød Anita, Børresen-Dale Anne-Lise

Abstract excerpt

Breast and ovarian cancers are the second and fifth leading causes of cancer deaths among women. Both breast and ovarian cancers are highly heterogeneous and are presented with diverse morphology, natural history, and response to therapy. In recent years, international efforts have led to extensive molecular characterization of both breast and ovarian tumors and identified biologically and clinically relevant...

Topics

Breast Neoplasms
Female
Gene Expression Regulation, Neoplastic
Humans
Mutation
Ovarian Neoplasms
Tumor Suppressor Protein p53

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 27815305
DOI: 10.1101/cshperspect.a026252
PMCID: PMC5204332

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