Protein phosphatase 1 activity in Drosophila mutants with abnormalities in mitosis and chromosome condensation.

doi:10.1016/0014-5793(90)81434-p

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Article

Protein phosphatase 1 activity in Drosophila mutants with abnormalities in mitosis and chromosome condensation.

FEBS letters - 26 Nov 1990

Dombrádi V, Axton J M, Barker H M, Cohen P T

Abstract excerpt

A Drosophila gene encoding a protein phosphatase 1 (PP1) has been sequenced, and lethal mutations in this locus (87B) analysed. Two mutants (ck19e211 and ck19hs46), which disrupt mitosis, lack the 87B isoenzyme and express only approximately 20% of wild type PP1 activity. The promoter region of t...

Topics

Amino Acid Sequence
Animals
Base Sequence
Cell Cycle
Chromosomes
Cloning, Molecular
Drosophila melanogaster
Genes
Larva
Mitosis
Molecular Sequence Data
Mutation
Phosphoprotein Phosphatases
Protein Phosphatase 1

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