Article
Protein phosphatase 1 activity in Drosophila mutants with abnormalities in mitosis and chromosome condensation.
FEBS letters - 26 Nov 1990
Dombrádi V, Axton J M, Barker H M, Cohen P T
Abstract excerpt
A Drosophila gene encoding a protein phosphatase 1 (PP1) has been sequenced, and lethal mutations in this locus (87B) analysed. Two mutants (ck19e211 and ck19hs46), which disrupt mitosis, lack the 87B isoenzyme and express only approximately 20% of wild type PP1 activity. The promoter region of the gene is deleted in the ck19e211 mutant. A third mutant (ck19e078), which shows suppression of position effect...
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