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Article

One of the protein phosphatase 1 isoenzymes in Drosophila is essential for mitosis.

Cell - 5 Oct 1990

Axton J M, Dombrádi V, Cohen P T, Glover D M

Abstract excerpt

Drosophila has four loci encoding type 1 protein serine/threonine phosphatases (PP1s). Here we describe mutations in one of these genes, at 87B on chromosome 3. Mutants die at the larval-pupal boundary with little or no imaginal cell proliferation. Neuroblasts are delayed in progress through mitosis and show defective spindle organization, abnormal sister chromatid segregation, hyperploidy, and excessive...

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PMID: 2170019
DOI: 10.1016/0092-8674(90)90286-n

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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One of the protein phosphatase 1 isoenzymes in Drosophila is essential for mitosis.PMID 2170019Read ↗

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