One of the protein phosphatase 1 isoenzymes in Drosophila is essential for mitosis.

doi:10.1016/0092-8674(90)90286-n

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Article

One of the protein phosphatase 1 isoenzymes in Drosophila is essential for mitosis.

Cell - 5 Oct 1990

Axton J M, Dombrádi V, Cohen P T, Glover D M

Abstract excerpt

Drosophila has four loci encoding type 1 protein serine/threonine phosphatases (PP1s). Here we describe mutations in one of these genes, at 87B on chromosome 3. Mutants die at the larval-pupal boundary with little or no imaginal cell proliferation. Neuroblasts are delayed in progress through mito...

Topics

Alleles
Animals
Chromosome Aberrations
Chromosome Mapping
Chromosomes
DNA
Drosophila
Female
Isoenzymes
Male
Mitosis
Mutation
Neurons
Phosphoprotein Phosphatases
Protein Phosphatase 1
Salivary Glands
Spindle Apparatus
Transcription, Genetic

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