Article
Type 1 protein phosphatase is required for maintenance of cell wall integrity, morphogenesis and cell cycle progression in Saccharomyces cerevisiae.
Journal of cell science - 1 Feb 2000
Andrews P D, Stark M J
Abstract excerpt
GLC7 encodes the catalytic subunit of type 1 protein serine/threonine phosphatase (PP1) in the yeast Saccharomyces cerevisiae. Here we have characterized the temperature-sensitive glc7-10 allele, which displays aberrant bud morphology and an abnormal actin cytoskeleton at the restrictive temperature. At 37 degrees C glc7-10 strains accumulated a high proportion of budded cells with an unmigrated nucleus,...
Topics
- Amino Acid Substitution
- Cell Cycle
- Cell Polarity
- Cell Wall
- Culture Media
- Cytoskeleton
- Fungal Proteins
- Genes, Fungal
- MAP Kinase Signaling System
- Morphogenesis
- Mutation
- Osmolar Concentration
- Phosphoprotein Phosphatases
- Phosphorylation
- Protein Kinase C
- Protein Processing, Post-Translational
- Saccharomyces cerevisiae
- Sorbitol