Article
Protein phosphatases and cell division cycle control.
Ciba Foundation symposium - 1 Jan 1992
Yanagida M, Kinoshita N, Stone E M, Yamano H
Abstract excerpt
Fission yeast has at least ten protein phosphatase genes that appear to play distinct roles in cell cycle control. Because of functional overlap, a clear lethal phenotype can be obtained only after multiple genetic alterations. Cells that have lost the protein phosphatase 1 (PP1)-like dis2/sds21 phosphatase activities prematurely enter mitosis and remain in a defective mitotic state with high H1 kinase activity...
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