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Article

Ypi1, a positive regulator of nuclear protein phosphatase type 1 activity in Saccharomyces cerevisiae.

Molecular biology of the cell - 1 Mar 2008

Bharucha Jennifer P, Larson Jennifer R, Gao Lu, Daves Lisa K, Tatchell Kelly

Abstract excerpt

The catalytic subunit of protein phosphatase type 1 (PP1) has an essential role in mitosis, acting in opposition to the Ipl1/Aurora B protein kinase to ensure proper kinetochore-microtubule interactions. However, the regulatory subunit(s) that completes the PP1 holoenzyme that functions in this capacity is not known. We show here that the budding yeast Ypi1 protein is a nuclear protein that functions with PP1...

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Identifiers

PMID: 18172024
DOI: 10.1091/mbc.e07-05-0499
PMCID: PMC2262978

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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