Motor phenotype of LRRK2 G2019S carriers in early-onset Parkinson disease.

doi:10.1001/archneurol.2009.267

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Article

Motor phenotype of LRRK2 G2019S carriers in early-onset Parkinson disease.

Archives of neurology - 1 Dec 2009

Alcalay Roy N, Mejia-Santana Helen, Tang Ming Xin, Rosado Llency, Verbitsky Miguel, Kisselev Sergey, Ross Barbara M, Louis Elan D, Comella Cynthia L, Colcher Amy, Jennings Danna, Nance Martha A, Bressman Susan, Scott William K, Tanner Caroline, Mickel Susan F, Andrews Howard F, Waters Cheryl H, Fahn Stanley, Cote Lucien J, Frucht Steven J, Ford Blair, Rezak Michael, Novak Kevin, Friedman Joseph H, Pfeiffer Ronald, Marsh Laura, Hiner Bradley, Siderowf Andrew, Caccappolo Elise, Ottman Ruth, Clark Lorraine N, Marder Karen S

Abstract excerpt

OBJECTIVE: To determine the motor phenotype of LRRK2 G2019S mutation carriers. LRRK2 mutation carriers were previously reported to manifest the tremor dominant motor phenotype, which has been associated with slower motor progression and less cognitive impairment compared with the postural instabi...

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Identifiers

PMID: 20008657
DOI: 10.1001/archneurol.2009.267
PMCID: PMC2837584

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20008657-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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