Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Skin colour and skin cancer - MC1R, the genetic link.

Melanoma research - 1 Oct 2002

Sturm R A

Abstract excerpt

Pigmentary traits such as red hair, fair skin, lack of tanning ability and propensity to freckle (the RHC phenotype) have been identified as genetic risk factors for both melanoma and non-melanocytic skin cancers when combined with the environmental risk factor of high ultraviolet light exposure. The human melanocortin-1 receptor (MC1R) is a key determinant of the pigmentation process and can account in large...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aspartic Acid
Share to Cystine
Share to Receptors, Corticotropin

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Receptors, Melanocortin

Share to Skin Pigmentation

Share to Tryptophan

Share to Twins, Dizygotic

Source

Identifiers

PMID: 12394181
DOI: 10.1097/00008390-200209000-00001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Skin colour and skin cancer - MC1R, the genetic link.PMID 12394181Read ↗

The melanocortin-1 receptor gene polymorphism and association with human skin cancer.Semantic proximity Read ↗

Melanocortin 1 receptor variants: functional role and pigmentary associations.Semantic proximity Read ↗

Melanocortin 1 receptor variants, pigmentation, and skin cancer susceptibility.Semantic proximity Read ↗

Melanocortin-1 receptor polymorphisms and risk of melanoma: is the association explained solely by pigmentation phenotype?Semantic proximity Read ↗

Comprehensive evaluation of allele frequency differences of MC1R variants across populations.Semantic proximity Read ↗

The role of melanocortin-1 receptor polymorphism in skin cancer risk phenotypes.Semantic proximity Read ↗

Melanocortin 1 receptor variants in an Irish population.Semantic proximity Read ↗

Defining the quantitative contribution of the melanocortin 1 receptor (MC1R) to variation in pigmentary phenotype.Semantic proximity Read ↗

Melanocortin receptors, red hair, and skin cancer.Semantic proximity Read ↗

Population-based study of natural variation in the melanocortin-1 receptor gene and melanoma.Semantic proximity Read ↗

Genetics of hair and skin color.Semantic proximity Read ↗

Melanocortin-1 receptor gene variants determine the risk of nonmelanoma skin cancer independently of fair skin and red hair.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.