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Article

Occurrence of Aurora A positive multipolar mitoses in distinct molecular classes of colorectal carcinomas and effect of Aurora A inhibition.

Molecular carcinogenesis - 1 Sept 2012

Herz Corinna, Schlürmann Fabienne, Batarello Daniela, Fichter Christiane D, Schöpflin Anja, Münch Claudia, Hauschke Dieter, Werner Martin, Lassmann Silke

Abstract excerpt

Aurora A "over-"expression may induce supernumerary centrosomes, respective multipolar mitoses, and aneuploidy. Here, we examined Aurora A positive multipolar mitoses in aneuploid, microsatellite-stable (MSS, "CIN-type") versus near-diploid, microsatellite-instable (MSI, "MIN-type") colorectal carcinomas (CRC) and CRC cell lines as well as the effect of Aurora A inhibition in CRC cell lines. In situ,...

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PMID: 21739483
DOI: 10.1002/mc.20823

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DLD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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