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Article

Aurora-A Expression Is Independently Associated with Chromosomal Instability in Colorectal Cancer

1 May 2009

Abstract excerpt

AURKA (the official symbol for Aurora-A, STK15, or BTAK) regulates the function of centrosomes, spindles, and kinetochores for proper mitotic progression. AURKA overexpression is observed in various cancers including colon cancer, and a link between AURKA and chromosomal instability (CIN) has been proposed. However, no study has comprehensively examined AURKA expression in relation to CIN or prognosis using a...

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PMID: 19412426
DOI: 10.1593/neo.09154

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Aurora-A Expression Is Independently Associated with Chromosomal Instability in Colorectal CancerPMID 19412426Read ↗

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