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Article

Occurrence of multipolar mitoses and association with Aurora-A/-B kinases and p53 mutations in aneuploid esophageal carcinoma cells.

BMC cell biology - 6 Apr 2011

Fichter Christiane D, Herz Corinna, Münch Claudia, Opitz Oliver G, Werner Martin, Lassmann Silke

Abstract excerpt

BACKGROUND: Aurora kinases and loss of p53 function are implicated in the carcinogenesis of aneuploid esophageal cancers. Their association with occurrence of multipolar mitoses in the two main histotypes of aneuploid esophageal squamous cell carcinoma (ESCC) and Barrett's adenocarcinoma (BAC) remains unclear. Here, we investigated the occurrence of multipolar mitoses, Aurora-A/-B gene copy numbers and...

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Identifiers

PMID: 21470402
DOI: 10.1186/1471-2121-12-13
PMCID: PMC3094318

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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