Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Proton Magnetic Resonance Spectroscopy in 22q11 Deletion Syndrome

30 Jun 2011

Abstract excerpt

OBJECTIVE: People with velo-cardio-facial syndrome or 22q11 deletion syndrome (22q11DS) have behavioral, cognitive and psychiatric problems. Approximately 30% of affected individuals develop schizophrenia-like psychosis. Glutamate dysfunction is thought to play a crucial role in schizophrenia. However, it is unknown if and how the glutamate system is altered in 22q11DS. People with 22q11DS are vulnerable for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Congenital heart defects research
Share to Fetal and Pediatric Neurological Disorders
Share to Genomic variations and chromosomal abnormalities

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21738766
DOI: 10.1371/journal.pone.0021685

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Proton Magnetic Resonance Spectroscopy in 22q11 Deletion SyndromePMID 21738766Read ↗

22q11 deletion syndrome: a review of the neuropsychiatric features and their neurobiological basisSemantic proximity Read ↗

Neuroimaging correlates of 22q11.2 deletion syndrome: implications for schizophrenia research.Semantic proximity Read ↗

Review: Genes Involved in Mitochondrial Physiology Within 22q11.2 Deleted Region and Their Relevance to SchizophreniaSemantic proximity Read ↗

Mitochondrial Citrate Transporter-dependent Metabolic Signature in the 22q11.2 Deletion SyndromeSemantic proximity Read ↗

Glutamatergic function in a genetic high-risk group for psychosis: A proton magnetic resonance spectroscopy study in individuals with 22q11.2 deletion.Semantic proximity Read ↗

Proline affects brain function in 22q11DS children with the low activity COMT 158 allele.Semantic proximity Read ↗

Dopamine dysfunction in 22q11 deletion syndrome: possible cause of motor symptoms.Semantic proximity Read ↗

Transcriptional and behavioral interaction between 22q11.2 orthologs modulates schizophrenia-related phenotypes in mice.Semantic proximity Read ↗

The molecular genetics of the 22q11-associated schizophrenia.Semantic proximity Read ↗

PRODH rs450046 and proline x COMT Val¹⁵⁸ Met interaction effects on intelligence and startle in adults with 22q11 deletion syndrome.Semantic proximity Read ↗

Genome-wide association study of NMDA receptor coagonists in human cerebrospinal fluid and plasma.Semantic proximity Read ↗

Excitatory inhibitory imbalance underlies hippocampal atrophy in individuals with 22q11.2 Deletion Syndrome with psychotic symptomsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.