Article
Neuroimaging correlates of 22q11.2 deletion syndrome: implications for schizophrenia research.
Current topics in medicinal chemistry - 1 Jan 2012
Boot E, van Amelsvoort T A M J
Abstract excerpt
22q11.2 Deletion syndrome (22q11DS) is the most common known recurrent copy-number variant disorder. It is also the most common known genetic risk factor for schizophrenia. The greater homogeneity of subjects with schizophrenia in 22q11DS compared with schizophrenia in the wider non-deleted population may help to identify much needed information on neuroanatomical substrates, and neurochemical and neurofunctional...
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