Article
Targeted overexpression of Drosophila transglutaminase-B induced characteristic phenotypes in a manner similar to transglutaminase-a.
Bioscience, biotechnology, and biochemistry - 1 Jan 2011
Ichikawa Akira, Kotaki Makoto, Sahashi Ritsuko, Yoshioka Yasuhide, Yamaguchi Masamitsu, Ikura Koji
Abstract excerpt
The Drosophila transglutaminase gene (CG7356) encodes two transglutaminases, dTG-A and dTG-B. To understand the roles of dTG-B during the development of the fly, we examined phenotypes induced through ectopic expression of dTG-B. Overexpression of dTG-B induced rough eye and extra wing crossvein phenotypes. These phenotypes were similar to those observed in the case of targeted overexpression of dTG-A.
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