Article
Overexpression of transglutaminase in the Drosophila wing imaginal disc induced an extra wing crossvein phenotype.
Bioscience, biotechnology, and biochemistry - 1 Jan 2010
Ichikawa Akira, Yamada Ayako, Sakamoto Harunobu, Umehara Masaru, Yoshioka Yasuhide, Yamaguchi Masamitsu, Ikura Koji
Abstract excerpt
To determine the roles of Drosophila transglutaminase-A (dTG-A), we examined a phenotype induced through ectopic expression of dTG-A. Overexpression of dTG-A in the wing imaginal disc induced an extra wing crossvein phenotype. This phenotype was suppressed by crossing with epidermal growth factor receptor (Egfr) signaling pathway mutant flies. These results indicate that this phenotype, induced by dTG-A, is...
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