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Article

Identification of the Drosophila core 1 beta1,3-galactosyltransferase gene that synthesizes T antigen in the embryonic central nervous system and hemocytes.

Glycobiology - 1 Dec 2008

Yoshida Hideki, Fuwa Takashi J, Arima Mikiko, Hamamoto Hiroshi, Sasaki Norihiko, Ichimiya Tomomi, Osawa Ken-Ichi, Ueda Ryu, Nishihara Shoko

Abstract excerpt

T antigen (Galbeta1-3GalNAcalpha1-Ser/Thr), the well-known tumor-associated antigen, is a core 1 mucin-type O-glycan structure that is synthesized by core 1 beta1,3-galactosyltransferase (C1beta3GalT), which transfers Gal from UDP-Gal to Tn antigen (GalNAcalpha1-Ser/Thr). Three putative C1beta3GalTs have been identified in Drosophila. However, although all three are expressed in embryos, their roles during...

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PMID: 18824562
DOI: 10.1093/glycob/cwn094

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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