Article
Over-expression of transglutaminase in the Drosophila eye imaginal disc induces a rough eye phenotype.
Molecular and cellular biochemistry - 1 Sept 2010
Umehara Masaru, Ichikawa Akira, Sakamoto Harunobu, Yamada Ayako, Yoshioka Yasuhide, Yamaguchi Masamitsu, Ikura Koji
Abstract excerpt
Transglutaminases (TGs) catalyze the cross-linking of proteins and are involved in various biological processes in mammals. In invertebrates, except for the involvement in the hemolymph clotting, the functions of TG have not been revealed. Drosophila has a single TG gene (CG7356), from which two kinds of mRNAs (dTG-RA and dTG-RB) are formed. RT-PCR analyses indicated that both dTGs-RA and -RB are synthesized in...
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