Article
Structural factors modulate the activity of antigenic poliovirus sequences expressed on hybrid hepatitis B surface antigen particles.
Journal of virology - 1 Dec 1990
Delpeyroux F, Van Wezel E, Blondel B, Crainic R
Abstract excerpt
We have studied the functional expression of antigenic poliovirus fragments carried by various hybrid hepatitis B surface antigen (HBsAg) particles. Several constructions were made by using two different insertion sites in the HBsAg molecule (amino acid positions 50 and 113) and two different sequences, one derived from poliovirus type 1 (PV-1) and the other from PV-2. The inserted fragments each encompassed...
Topics
- Amino Acid Sequence
- Animals
- Antibodies, Monoclonal
- Antigens, Viral
- Base Sequence
- Enzyme-Linked Immunosorbent Assay
- Genetic Variation
- Hepatitis B Surface Antigens
- L Cells
- Mice
- Molecular Sequence Data
