Illegitimate and homologous recombination in mammalian cells: differential sensitivity to an inhibitor of poly(ADP-ribosylation).

doi:10.1093/nar/18.20.5981

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Article

Illegitimate and homologous recombination in mammalian cells: differential sensitivity to an inhibitor of poly(ADP-ribosylation).

Nucleic acids research - 25 Oct 1990

Waldman B C, Waldman A S

Abstract excerpt

We determined the effect of 3-methoxybenzamide (3-MB), a competitive inhibitor of poly(ADP-ribose)polymerase (E.C. 2.4.2.30), on illegitimate and extrachromosomal homologous recombination in mouse Ltk- cells. Cells were transfected with a wild type Herpes thymidine kinase (tk) gene or with two de...

Topics

Animals
Benzamides
Cell Division
Cell Survival
Genes, Viral
L Cells
Mice
Mutation
Plasmids
Poly(ADP-ribose) Polymerase Inhibitors
Recombination, Genetic
Simplexvirus
Thymidine Kinase
Transfection
Viral Structural Proteins

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