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Article

Illegitimate and homologous recombination in mammalian cells: differential sensitivity to an inhibitor of poly(ADP-ribosylation).

Nucleic acids research - 25 Oct 1990

Waldman B C, Waldman A S

Abstract excerpt

We determined the effect of 3-methoxybenzamide (3-MB), a competitive inhibitor of poly(ADP-ribose)polymerase (E.C. 2.4.2.30), on illegitimate and extrachromosomal homologous recombination in mouse Ltk- cells. Cells were transfected with a wild type Herpes thymidine kinase (tk) gene or with two defective tk gene sequences followed by selection for tk-positive colonies. Using a wild type tk gene, colony formation...

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Identifiers

PMID: 2172923
DOI: 10.1093/nar/18.20.5981
PMCID: PMC332394

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Source receipt: pubmed, retrieved 7 Sept 2026.

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