A novel selection system for recombinational and mutational events within an intron of a eucaryotic gene.

doi:10.1093/nar/18.17.5173

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Article

A novel selection system for recombinational and mutational events within an intron of a eucaryotic gene.

Nucleic acids research - 11 Sept 1990

Porter T, Pennington S L, Adair G M, Nairn R S, Wilson J H

Abstract excerpt

In order to identify a poison sequence that might be useful in studying illegitimate recombination of mammalian cell chromosomes, several DNA segments were tested for their ability to interfere with gene expression when placed in an intron. A tRNA gene and its flanking sequences (267 bp) were sho...

Topics

Adenine Phosphoribosyltransferase
Animals
Antigens, Viral, Tumor
Base Sequence
Cell Line
Gene Expression Regulation
Gene Expression Regulation, Enzymologic
Genes
Genes, Viral
Haplorhini
Introns
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

RNA, Transfer

Recombination, Genetic

Simian virus 40

Transfection

Virus Replication

Source

Open in PubMed Open full text

Identifiers

PMID: 2169607
DOI: 10.1093/nar/18.17.5173
PMCID: PMC332139

Genes

APRT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2169607-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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