Article
Extrachromosomal recombination occurs efficiently in cells defective in various DNA repair systems.
Nucleic acids research - 1 Jun 1996
Morrison C, Wagner E
Abstract excerpt
A series of different frameshift mutations of a firefly luciferase reporter plasmid was created so that no activity was obtained when they were transfected into mammalian cells. Co-transfection of these constructs with short fragments of the original sequence resulted in luciferase activity in different cell lines (A-549, NIH 3T3 and Jurkat). The level of this activity was dependent on the length of the fragment,...
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