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Article

Murine retroviral-induced spongiform neuronal degeneration parallels resident microglial cell infection: ultrastructural findings.

Laboratory investigation; a journal of technical methods and pathology - 1 Nov 1990

Baszler T V, Zachary J F

Abstract excerpt

Ts1 Moloney murine leukemia virus (MoMuLV) is a neurovirulent retrovirus that causes a progressive, noninflammatory, spongiform, neurodegenerative disease in mice. The temporal localization of cellular targets for virus replication and the genesis of ultrastructural spongiform changes in the central nervous system (CNS) of CFW/D mice inoculated at birth with neurovirulent ts1 MoMuLV and nonneurovirulent wild type...

Topics

Animals
Central Nervous System Diseases
Leukemia Virus, Murine
Mice
Mice, Inbred Strains
Mutation
Nerve Degeneration
Neuroglia
Spleen
Virus Replication

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 2172651

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2172651-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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