Article
Interaction between endoplasmic reticulum stress and caspase 8 activation in retrovirus MoMuLV-ts1-infected astrocytes.
Virology - 10 May 2006
Liu Na, Scofield Virginia L, Qiang Wenan, Yan Mingshan, Kuang Xianghong, Wong Paul K Y
Abstract excerpt
The murine retrovirus, MoMuLV-ts1, induces progressive paralysis and immune deficiency in FVB/N mice. We have reported previously that ts1 infection causes apoptosis in astrocytes via endoplasmic reticulum (ER) and mitochondrial stress (Liu, N., Kuang, X., Kim, H.T., Stoica, G., Qiang, W., Scofield, V.L., Wong, P.K.Y. Wong. 2004. Possible involvement of both endoplasmic reticulum- and mitochondria-dependent...
Topics
- Animals
- Apoptosis
- Astrocytes
- Caspase 8
- Caspases
- Cysteine Proteinase Inhibitors
- Endoplasmic Reticulum
- Enzyme Activation
- Membrane Proteins
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Models, Biological
- Moloney murine leukemia virus
