Article
Association between GT-repeat polymorphism at heme oxygenase-1 gene promoter and gastric cancer and metastasis.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jun 2015
Motovali-Bashi M, Hamidy M
Abstract excerpt
HO-1 gene encodes heme oxygenase-1 enzyme that catalyzes the oxidation of heme to carbon monoxide (CO). It has also been suggested that cells could be protected by the enzyme against stress. A (GT) n dinucleotide repeat at HO-1 promoter is a polymorphic region and modulates gene transcription and associated with some of diseases. In this study, length of polymorphism GT tandem repeat has been determined and...
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