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Article

Heme oxygenase-1 gene promoter polymorphism and the risk of pediatric nonalcoholic fatty liver disease.

International journal of obesity (2005) - 1 Aug 2015

Chang P-F, Lin Y-C, Liu K, Yeh S-J, Ni Y-H

Abstract excerpt

BACKGROUND AND OBJECTIVES: Oxidative stress and the insulin-resistant state are thought to be key components in the pathogenesis of pediatric nonalcoholic fatty liver disease (NAFLD). Heme oxygenase (HO) is important in the defense against oxidative stress. This study aimed to assess the association of HO-1 gene promoter polymorphism and insulin resistance with NAFLD among obese children. METHODS: A total of 101...

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PMID: 25835554
DOI: 10.1038/ijo.2015.46

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