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Article

The pathogenic role of cystathionine γ-lyase/hydrogen sulfide in streptozotocin-induced diabetes in mice.

The American journal of pathology - 1 Aug 2011

Yang Guangdong, Tang Guanghua, Zhang Ling, Wu Lingyun, Wang Rui

Abstract excerpt

Reduced β-cell mass and increased activities of ATP-sensitive K(+) channels in pancreatic β cells are associated with the pathogenesis of diabetes. Cystathionine γ-lyase (CSE) is a major hydrogen sulfide (H(2)S)-producing enzyme in pancreatic β cells. Herein, we examine the effects of genetic and...

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Identifiers

PMID: 21718679
DOI: 10.1016/j.ajpath.2011.04.028
PMCID: PMC3157274

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21718679-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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