Article
A viable mouse polyomavirus mutant without immortalizing or transforming activities.
Virology - 1 Nov 1990
Linder S, Nilsson M, Martens I, Magnusson G
Abstract excerpt
The polyomavirus mutant, dl1041, has a 375-base pair deletion. It removes most of the sequences that are unique to rodent polyomaviruses and encodes part of the large and middle T-antigens. The mutant was conditionally viable, although both the immortalizing and transforming functions of the T-an...
Topics
- Animals
- Antigens, Polyomavirus Transforming
- Cell Line
- Cell Transformation, Neoplastic
- Cell Transformation, Viral
- Cells, Cultured
- Chromosome Deletion
- DNA Replication
- Genes, Viral
- Mice
- Mutation
- Polyomavirus