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Article

Mouse Papillomavirus L1 and L2 Are Dispensable for Viral Infection and Persistence at Both Cutaneous and Mucosal Tissues.

Viruses - 14 Sept 2021

Brendle Sarah, Li Jingwei J, Cladel Nancy M, Shearer Debra A, Budgeon Lynn R, Balogh Karla K, Atkins Hannah, Costa-Fujishima Marina, Lopez Paul, Christensen Neil D, Doorbar John, Murooka Thomas T, Hu Jiafen

Abstract excerpt

Papillomavirus L1 and L2, the major and minor capsid proteins, play significant roles in viral assembly, entry, and propagation. In the current study, we investigate the impact of L1 and L2 on viral life cycle and tumor growth with a newly established mouse papillomavirus (MmuPV1) infection model. MmuPV1 L1 knockout, L2 knockout, and L1 plus L2 knockout mutant genomes (designated as L1ATGko-4m, L2ATGko, and...

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Share to Capsid Proteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34578405
DOI: 10.3390/v13091824
PMCID: PMC8473024

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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