Article
[Allelic losses on chromosomes 1p, 3p, 11p, 11q in non small cell lung cancers].
Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie - 1 Jan 1990
Cheng J Q, Crépin M, Hamelin R
Abstract excerpt
Recent studies have shown that lung cancer patients frequently suffer inactivation of antioncogenes such as Rb gene (13q14) and p53 gene (17p13). In a study of 48 cases of non-small cell lung cancer (28 squamous-cell carcinomas, 11 adenocarcinomas, 4 large-cell carcinomas, and 5 other types) using restriction fragment length polymorphism analysis, we found DNA sequence deletions from chromosomes 1p32-36, 3p21,...
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