[Genetic abnormalities in lung cancer and their prognostic implications].

Article

[Genetic abnormalities in lung cancer and their prognostic implications].

Gan to kagaku ryoho. Cancer & chemotherapy - 1 Jul 1996

Mitsudomi T, Takahashi T

Abstract excerpt

Recent advances in molecular biology have revealed various genetic lesions in lung cancer. Mutations of the K-ras gene, amplification or overexpression of myc family genes, erbB2 gene, or bcl2 gene are frequent genetic changes of oncogenes in lung cancer. Inactivation of tumor suppressor genes su...

Topics

Genes, Retinoblastoma
Genes, erbB-2
Genes, myc
Genes, p53
Genes, ras
Humans
Lung Neoplasms
Mutation
Prognosis
Proto-Oncogene Proteins
Proto-Oncogene Proteins c-bcl-2
Survival Rate

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