Article
Klotho locus, metabolic traits, and serum hemoglobin in hospitalized older patients: a genetic association analysis.
Age (Dordrecht, Netherlands) - 1 Aug 2012
Paroni Giulia, Seripa Davide, Panza Francesco, Addante Filomena, Copetti Massimiliano, D'Onofrio Grazia, Pellegrini Fabio, Fontana Luigi, Pilotto Alberto
Abstract excerpt
Klotho (KL) gene has been involved in severe alterations of physiological biochemical parameters leading to premature aging-like phenotypes and strikingly shortening lifespan. KL participates to the regulation of a number of intracellular biochemical pathways, including lipid profile and glucose metabolism. Aim of this study was to investigate the possible association between KL locus and biological parameters...
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