Article
The association of Klotho gene polymorphism with the mortality of patients on maintenance dialysis.
Clinical nephrology - 1 Oct 2013
Ko Gang Jee, Lee Young Mo, Lee Eun A, Lee Ji Eun, Bae So Yon, Park Sang Won, Park Man Sik, Pyo Heui Jung, Kwon Young Joo
Abstract excerpt
Despite medical progress, high morbidity and mortality rates have persisted in patients with end-stage renal disease (ESRD). The role in atherosclerosis and cardiovascular disease of klotho, an aging process-related gene, has been highlighted. Genetic variation in klotho has been reported to be a risk factor for coronary artery disease and ischemic stroke. Regarding the significance of cardiovascular disease for...
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