Article
Diversification at transcription factor binding sites within a species and the implications for environmental adaptation.
Molecular biology and evolution - 1 Dec 2011
Ames Ryan M, Lovell Simon C
Abstract excerpt
Evolution of new cellular functions can be achieved both by changes in protein coding sequences and by alteration of expression patterns. Variation of expression may lead to changes in cellular function with relatively little change in genomic sequence. We therefore hypothesize that one of the first signals of functional divergence should be evolution of transcription factor-binding sites (TFBSs). This adaptation...
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