Accumulation of cis- and trans-regulatory variations is associated with phenotypic divergence of a complex trait between yeast species.

Abstract excerpt

Gene regulatory variations accumulate during evolution and alter gene expression. While the importance of expression variation in phenotypic evolution is well established, the molecular basis remains largely unknown. Here, we examine two closely related yeast species, Saccharomyces cerevisiae and Saccharomyces paradoxus, which show phenotypical differences in morphology and cell cycle progression when grown in...

Topics

• Cell Cycle Proteins
• Evolution, Molecular
• Forkhead Transcription Factors
• Gene Expression Regulation, Fungal
• Multifactorial Inheritance
• Phenotype
• Phylogeny
• Saccharomyces
• Saccharomyces cerevisiae
• Saccharomyces cerevisiae Proteins