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Article

The evolution of transcriptional regulation in eukaryotes.

Molecular biology and evolution - 1 Sept 2003

Wray Gregory A, Hahn Matthew W, Abouheif Ehab, Balhoff James P, Pizer Margaret, Rockman Matthew V, Romano Laura A

Abstract excerpt

Gene expression is central to the genotype-phenotype relationship in all organisms, and it is an important component of the genetic basis for evolutionary change in diverse aspects of phenotype. However, the evolution of transcriptional regulation remains understudied and poorly understood. Here we review the evolutionary dynamics of promoter, or cis-regulatory, sequences and the evolutionary mechanisms that...

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Source

Identifiers

PMID: 12777501
DOI: 10.1093/molbev/msg140

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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