The emergence of mouse models of atherosclerosis and their relevance to clinical research

Abstract excerpt

Smith JD, Breslow JL (Laboratory of Biochemical Genetics and Metabolism, The Rockefeller University, New York, NY, USA). The emergence of mouse models of atherosclerosis and their relevance to clinical research (Review). J Intern Med 1997; 242 : 99–109. Due to the ability to introduce or mutate genes, the mouse has become the most common experimental animal model for atherosclerosis research. Wildtype mice on a...

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